Potassium Cation → 2,2-Diphenyl-4-piperidin-1-ylbutanenitrile

HRID 934063Notes

Reaction equation

HRID 934063 reaction equation
[CH2:1]1[CH2:2][CH2:3][NH:4][CH2:5][CH2:6]1.[I-:8].[K+:10].[K+:7].[OH-:9].[OH2:29].[c:11]1([C:17]([C:18]#[N:19])([CH2:20][CH2:21][Br:22])[c:23]2[cH:24][cH:25][cH:26][cH:27][cH:28]2)[cH:12][cH:13][cH:14][cH:15][cH:16]1>>[CH2:1]1[CH2:2][CH2:3][N:4]([CH2:21][CH2:20][C:17]([c:11]2[cH:12][cH:13][cH:14][cH:15][cH:16]2)([C:18]#[N:19])[c:23]2[cH:24][cH:25][cH:26][cH:27][cH:28]2)[CH2:5][CH2:6]1

Participants

7

Reactant 6

HCID 813Potassium Cation2×HCID 961HydroxideHCID 962WaterHCID 8082PiperidineHCID 30165Iodide IonHCID 965754-Bromo-2,2-diphenylbutyronitrile

Product 1

HCID 2245772,2-Diphenyl-4-piperidin-1-ylbutanenitrile

Sources & evidence

ORD record
ord-52c4301a1e04497ab1694710191dc3ad
Source dataset
Validation data from https://doi.org/10.1039/C8SC04228D

Reaction notes

Loading…