Water → 1-(tert-Butoxycarbonyl)-4-(methanesulfonyloxy)piperidine

HRID 934197Notes

Reaction equation

HRID 934197 reaction equation
[C:1](=[O:2])([O:3][C:4]([CH3:5])([CH3:6])[CH3:7])[N:8]1[CH2:9][CH2:10][CH:11]([OH:14])[CH2:12][CH2:13]1.[CH3:15][CH2:16][N:17]([CH2:18][CH3:19])[CH2:20][CH3:21].[CH3:22][S:23]([Cl:24])(=[O:25])=[O:26].[CH3:28][c:29]1[cH:30][cH:31][cH:32][cH:33][cH:34]1.[OH2:27]>>[C:1](=[O:2])([O:3][C:4]([CH3:5])([CH3:6])[CH3:7])[N:8]1[CH2:9][CH2:10][CH:11]([O:14][S:23]([CH3:22])(=[O:25])=[O:26])[CH2:12][CH2:13]1

Participants

6

Reactant 5

HCID 962WaterHCID 1140TolueneHCID 8471TriethylamineHCID 31297Methanesulfonyl chlorideHCID 643502Tert-butyl 4-hydroxypiperidine-1-carboxylate

Product 1

HCID 41848691-(tert-Butoxycarbonyl)-4-(methanesulfonyloxy)piperidine

Sources & evidence

ORD record
ord-adb8b7ad62644f7ab1a4267bbfc06ffc
Source dataset
Validation data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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