Hydrochloric Acid → 5-Fluoro-2-iodobenzoic acid

HRID 934202Notes

Reaction equation

HRID 934202 reaction equation
[ClH:12].[I-:18].[K+:17].[N:13]([O-:14])=[O:15].[NH2:1][c:2]1[c:3]([C:4](=[O:5])[OH:6])[cH:7][c:8]([F:11])[cH:9][cH:10]1.[Na+:16].[Na+:29].[Na+:30].[OH2:31].[S:19](=[O:20])(=[O:21])([OH:22])[OH:23].[S:24]([O-:25])([O-:26])(=[O:27])=[S:28]>>[c:2]1([I:18])[c:3]([C:4](=[O:5])[OH:6])[cH:7][c:8]([F:11])[cH:9][cH:10]1

Participants

10

Reactant 9

HCID 313Hydrochloric AcidHCID 813Potassium CationHCID 923Sodium ion3×HCID 946NitriteHCID 962WaterHCID 1084Thiosulfate ionHCID 1118Sulfuric AcidHCID 30165Iodide IonHCID 1014122-Amino-5-fluorobenzoic acid

Product 1

HCID 131585835-Fluoro-2-iodobenzoic acid

Sources & evidence

ORD record
ord-095ebd6141d1447f99622b619570c0b8
Source dataset
Validation data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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