Hydrochloric Acid → 7-Oxo-4,5,6,7-tetrahydro-benzo[b]thiophene-3-sulfonic acid [2-(2,4-difluorophenyl)-2-hydroxy-ethyl]-amide

HRID 934217Notes

Reaction equation

HRID 934217 reaction equation
[ClH:15].[NH2:16][CH2:17][CH:18]([OH:19])[c:20]1[c:21]([F:27])[cH:22][c:23]([F:26])[cH:24][cH:25]1.[O:1]=[C:2]1[CH2:3][CH2:4][CH2:5][c:6]2[c:7]1[s:8][cH:9][c:10]2[S:11](=[O:12])(=[O:13])[Cl:14]>>[O:1]=[C:2]1[CH2:3][CH2:4][CH2:5][c:6]2[c:7]1[s:8][cH:9][c:10]2[S:11](=[O:12])(=[O:13])[NH:16][CH2:17][CH:18]([OH:19])[c:20]1[c:21]([F:27])[cH:22][c:23]([F:26])[cH:24][cH:25]1

Participants

4

Reactant 3

HCID 313Hydrochloric AcidHCID 167676572-Amino-1-(2,4-difluorophenyl)ethanolHCID 210986857-Oxo-4,5,6,7-tetrahydrobenzo[b]thiophene-3-sulfonyl chloride

Product 1

HCID 210986777-Oxo-4,5,6,7-tetrahydro-benzo[b]thiophene-3-sulfonic acid [2-(2,4-difluorophenyl)-2-hydroxy-ethyl]-amide

Sources & evidence

ORD record
ord-35d42e6146414d53abf07adcec60f7a5
Source dataset
Validation data from https://doi.org/10.1039/C8SC04228D

Reaction notes

Loading…