Potassium Cation → Tert-butyl 4-(2-methoxy-2-oxoethyl)piperazine-1-carboxylate

HRID 934429Notes

Reaction equation

HRID 934429 reaction equation
[Br:20][CH2:21][C:22](=[O:23])[O:24][CH3:25].[C:1](=[O:2])([O-:3])[O-:4].[C:7](=[O:8])([O:9][C:10]([CH3:11])([CH3:12])[CH3:13])[N:14]1[CH2:15][CH2:16][NH:17][CH2:18][CH2:19]1.[CH3:26][C:27]#[N:28].[K+:5].[K+:6]>>[C:7](=[O:8])([O:9][C:10]([CH3:11])([CH3:12])[CH3:13])[N:14]1[CH2:15][CH2:16][N:17]([CH2:21][C:22](=[O:23])[O:24][CH3:25])[CH2:18][CH2:19]1

Participants

6

Reactant 5

HCID 813Potassium Cation2×HCID 6342AcetonitrileHCID 19660Carbonate IonHCID 60984Methyl bromoacetateHCID 143452tert-Butyl piperazine-1-carboxylate

Product 1

HCID 46785870Tert-butyl 4-(2-methoxy-2-oxoethyl)piperazine-1-carboxylate

Sources & evidence

ORD record
ord-e81d71717b0d4b3a82e5b94727633f66
Source dataset
Validation data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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