HRID934431

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID679

Dimethyl sulfoxide

C2H6OS

HCID887

Methanol

CH4O

HCID923

Sodium ion

Na+

HCID8028

Tetrahydrofuran

C4H8O

HCID24385

未命名化合物

HCID28123

Borohydride

BH4-

HCID58772878

未命名化合物

PRODUCTS

产物

HCID58772869

3-Fluoro-4-(2-(4-(methylsulfonyl)phenyl)thieno[3,2-b]pyridin-7-yloxy)benzenamine

C20H15FN2O3S2

来源与证据

来源类型: Open Reaction Database
ORD记录: ord-19ad6c3af418490db91d5a5088521e46
来源数据集: Validation data from https://doi.org/10.1039/C8SC04228D
DOI: 10.1039/C8SC04228D
来源说明: Validation data from https://doi.org/10.1039/C8SC04228D

反应SMILES

[BH4-:31].[CH2:37]1[O:38][CH2:39][CH2:40][CH2:41]1.[CH3:33][S:34]([CH3:35])=[O:36].[CH3:42][OH:43].[F:1][c:2]1[c:3]([O:4][c:5]2[c:6]3[c:7]([n:8][cH:9][cH:10]2)[cH:11][c:12](-[c:14]2[cH:15][cH:16][c:17]([S:20](=[O:21])(=[O:22])[CH3:23])[cH:18][cH:19]2)[s:13]3)[cH:24][cH:25][c:26]([N+:28]([O-:29])=[O:30])[cH:27]1.[Na+:32].[Ni:44]([Cl:45])[Cl:46]>>[F:1][c:2]1[c:3]([O:4][c:5]2[c:6]3[c:7]([n:8][cH:9][cH:10]2)[cH:11][c:12](-[c:14]2[cH:15][cH:16][c:17]([S:20](=[O:21])(=[O:22])[CH3:23])[cH:18][cH:19]2)[s:13]3)[cH:24][cH:25][c:26]([NH2:28])[cH:27]1