Dimethylformamide → Nerisopam

HRID 934930Notes

Reaction equation

HRID 934930 reaction equation
[CH3:26][N:27]([CH3:28])[CH:29]=[O:30].[N+:1]([O-:2])(=[O:3])[c:4]1[cH:5][cH:6][c:7]([C:10]2=[N:11][N:12]=[C:13]([CH3:25])[CH2:14][c:15]3[c:16]2[cH:17][c:18]([O:23][CH3:24])[c:19]([O:21][CH3:22])[cH:20]3)[cH:8][cH:9]1.[Pd:31]>>[NH2:1][c:4]1[cH:5][cH:6][c:7]([C:10]2=[N:11][N:12]=[C:13]([CH3:25])[CH2:14][c:15]3[c:16]2[cH:17][c:18]([O:23][CH3:24])[c:19]([O:21][CH3:22])[cH:20]3)[cH:8][cH:9]1

Participants

4

Reactant 3

HCID 6228DimethylformamideHCID 23938PalladiumHCID 20233113HCID 20233113, compound

Product 1

HCID 65875Nerisopam

Sources & evidence

ORD record
ord-8e0eb7d5cd5043f997254289250aaf15
Source dataset
Validation data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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