Dichloromethane → Tert-butyl 1-(1,4-dichloroisoquinolin-7-yl)sulfonylpiperidine-2-carboxylate

HRID 934937Notes

Reaction equation

HRID 934937 reaction equation
[CH3:30][CH2:31][N:32]([CH2:33][CH3:34])[CH2:35][CH3:36].[Cl:1][c:2]1[n:3][cH:4][c:5]([Cl:16])[c:6]2[cH:7][cH:8][c:9]([S:12](=[O:13])(=[O:14])[Cl:15])[cH:10][c:11]12.[Cl:37][CH2:38][Cl:39].[NH:17]1[CH:18]([C:23](=[O:24])[O:25][C:26]([CH3:27])([CH3:28])[CH3:29])[CH2:19][CH2:20][CH2:21][CH2:22]1>>[Cl:1][c:2]1[n:3][cH:4][c:5]([Cl:16])[c:6]2[cH:7][cH:8][c:9]([S:12](=[O:13])(=[O:14])[N:17]3[CH:18]([C:23](=[O:24])[O:25][C:26]([CH3:27])([CH3:28])[CH3:29])[CH2:19][CH2:20][CH2:21][CH2:22]3)[cH:10][c:11]12

Participants

5

Reactant 4

HCID 6344DichloromethaneHCID 8471TriethylamineHCID 4180856Tert-butyl piperidine-2-carboxylateHCID 166582941,4-Dichloroisoquinoline-7-sulfonyl chloride

Product 1

HCID 73300599Tert-butyl 1-(1,4-dichloroisoquinolin-7-yl)sulfonylpiperidine-2-carboxylate

Sources & evidence

ORD record
ord-9045953cf5f04135867ffa10a64694d2
Source dataset
Validation data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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