Tetrahydrofuran → 2-{3-[4-(2-tert-Butyl-6-cyclobutyl-pyrimidin-4-yl)-piperazin-1-yl]-propoxy}-pyrimidin-4-ol
Reaction equation
[CH2:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1)[O:8][c:9]1[n:10][c:11]([O:15][CH2:16][CH2:17][CH2:18][N:19]2[CH2:20][CH2:21][N:22]([c:25]3[n:26][c:27]([C:35]([CH3:36])([CH3:37])[CH3:38])[n:28][c:29]([CH:31]4[CH2:32][CH2:33][CH2:34]4)[cH:30]3)[CH2:23][CH2:24]2)[n:12][cH:13][cH:14]1.[O:39]1[CH2:40][CH2:41][CH2:42][CH2:43]1>>[OH:8][c:9]1[n:10][c:11]([O:15][CH2:16][CH2:17][CH2:18][N:19]2[CH2:20][CH2:21][N:22]([c:25]3[n:26][c:27]([C:35]([CH3:36])([CH3:37])[CH3:38])[n:28][c:29]([CH:31]4[CH2:32][CH2:33][CH2:34]4)[cH:30]3)[CH2:23][CH2:24]2)[n:12][cH:13][cH:14]1Participants
3
Sources & evidence
- ORD record
- ord-a61223313ae247ef99a88f5a9f0dfb9f
- Source dataset
- Validation data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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