Phosphorus oxychloride → Ethyl 4-chloro-2-phenylpyrimidine-5-carboxylate
Reaction equation
[P:19]([Cl:20])([Cl:21])([Cl:22])=[O:23].[c:1]1(-[c:7]2[n:8][cH:9][c:10]([C:14](=[O:15])[O:16][CH2:17][CH3:18])[c:11]([OH:13])[n:12]2)[cH:2][cH:3][cH:4][cH:5][cH:6]1>>[c:1]1(-[c:7]2[n:8][cH:9][c:10]([C:14](=[O:15])[O:16][CH2:17][CH3:18])[c:11]([Cl:21])[n:12]2)[cH:2][cH:3][cH:4][cH:5][cH:6]1Participants
3
Sources & evidence
- ORD record
- ord-550c169692054da8b3b39ad4a567dd13
- Source dataset
- Validation data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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