Toluene → 2-Morpholin-4-yl-5-nitro-benzoyl chloride

HRID 935083Notes

Reaction equation

HRID 935083 reaction equation
[CH3:28][c:29]1[cH:30][cH:31][cH:32][cH:33][cH:34]1.[O:19]=[CH:20][N:21]([CH3:22])[CH3:23].[O:1]1[CH2:2][CH2:3][N:4]([c:7]2[c:8]([C:9](=[O:10])[OH:11])[cH:12][c:13]([N+:16](=[O:17])[O-:18])[cH:14][cH:15]2)[CH2:5][CH2:6]1.[S:24]([Cl:25])([Cl:26])=[O:27]>>[O:1]1[CH2:2][CH2:3][N:4]([c:7]2[c:8]([C:9](=[O:10])[Cl:26])[cH:12][c:13]([N+:16](=[O:17])[O-:18])[cH:14][cH:15]2)[CH2:5][CH2:6]1

Participants

5

Reactant 4

HCID 1140TolueneHCID 6228DimethylformamideHCID 24386Thionyl ChlorideHCID 27257552-Morpholino-5-nitrobenzoic acid

Product 1

HCID 172741532-Morpholin-4-yl-5-nitro-benzoyl chloride

Sources & evidence

ORD record
ord-4a065298afae49c0a8f387af874b4cd3
Source dataset
Validation data from https://doi.org/10.1039/C8SC04228D

Reaction notes

Loading…