Dichloromethane → 1-(3-chloro-2-pyridinyl)-4-hydroxy-N-[4-(trifluoromethyl)phenyl]-4-piperidinecarboxamide
Reaction equation
[CH3:18][CH2:19][N:20]=[C:21]=[N:22][CH2:23][CH2:24][CH2:25][N:26]([CH3:27])[CH3:28].[Cl:1][c:2]1[c:3]([N:8]2[CH2:9][CH2:10][C:11]([C:14](=[O:15])[OH:16])([OH:17])[CH2:12][CH2:13]2)[n:4][cH:5][cH:6][cH:7]1.[Cl:40][CH2:41][Cl:42].[F:29][C:30]([c:31]1[cH:32][cH:33][c:34]([NH2:35])[cH:36][cH:37]1)([F:38])[F:39]>>[Cl:1][c:2]1[c:3]([N:8]2[CH2:9][CH2:10][C:11]([C:14](=[O:16])[NH:35][c:34]3[cH:33][cH:32][c:31]([C:30]([F:29])([F:38])[F:39])[cH:37][cH:36]3)([OH:17])[CH2:12][CH2:13]2)[n:4][cH:5][cH:6][cH:7]1Participants
5
Reactant 4
Product 1
Sources & evidence
- ORD record
- ord-a22844cbb4ee4e8cb8ddcdc9d5942479
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (2/10)
Reaction notes
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