Dichloromethane → N-methyl-N-(6-(6-(4-phenoxyphenylamino)pyrimidin-4-ylamino)pyridin-2-yl)acrylamide
Reaction equation
[C:30]([CH:31]=[CH2:32])(=[O:33])[Cl:34].[CH3:1][NH:2][c:3]1[cH:4][cH:5][cH:6][c:7]([NH:9][c:10]2[n:11][cH:12][n:13][c:14]([NH:16][c:17]3[cH:18][cH:19][c:20]([O:23][c:24]4[cH:25][cH:26][cH:27][cH:28][cH:29]4)[cH:21][cH:22]3)[cH:15]2)[n:8]1.[CH3:35][N:36]1[CH2:37][CH2:38][CH2:39][C:40]1=[O:41].[Cl:42][CH2:43][Cl:44]>>[CH3:1][N:2]([c:3]1[cH:4][cH:5][cH:6][c:7]([NH:9][c:10]2[n:11][cH:12][n:13][c:14]([NH:16][c:17]3[cH:18][cH:19][c:20]([O:23][c:24]4[cH:25][cH:26][cH:27][cH:28][cH:29]4)[cH:21][cH:22]3)[cH:15]2)[n:8]1)[C:30]([CH:31]=[CH2:32])=[O:33]Participants
5
Sources & evidence
- ORD record
- ord-6b16ee8f701341988522dcdab92f3ba0
- Source dataset
- Validation data from https://doi.org/10.1039/C8SC04228D
Reaction notes
Loading…