Hydrochloric Acid → N6-Hydroxy-N2-(3-methoxypropyl)-3,4-dihydroisoquinoline-2,6(1H)-dicarboxamide

HRID 935130Notes

Reaction equation

HRID 935130 reaction equation
[CH3:1][O:2][CH2:3][CH2:4][CH2:5][NH:6][C:7](=[O:8])[N:9]1[CH2:10][c:11]2[cH:12][cH:13][c:14]([C:19](=[O:20])[NH:21][O:22][CH:23]3[CH2:24][CH2:25][CH2:26][CH2:27][O:28]3)[cH:15][c:16]2[CH2:17][CH2:18]1.[CH3:30][OH:31].[ClH:29]>>[CH3:1][O:2][CH2:3][CH2:4][CH2:5][NH:6][C:7](=[O:8])[N:9]1[CH2:10][c:11]2[cH:12][cH:13][c:14]([C:19](=[O:20])[NH:21][OH:22])[cH:15][c:16]2[CH2:17][CH2:18]1

Participants

4

Reactant 3

HCID 313Hydrochloric AcidHCID 887MethanolHCID 86656594N2-(3-methoxypropyl)-N6-(tetrahydro-2H-pyran-2-yloxy)-3,4-dihydroisoquinoline-2,6(1H)-dicarboxamide

Product 1

HCID 44230392N6-Hydroxy-N2-(3-methoxypropyl)-3,4-dihydroisoquinoline-2,6(1H)-dicarboxamide

Sources & evidence

ORD record
ord-d9f588e9bb4845bdb1adb1569b3d3f75
Source dataset
Validation data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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