1-(2,3-difluorobenzyl)-1H-indazol-5-amine → Hydrochloric Acid

HRID 935197Notes

Reaction equation

HRID 935197 reaction equation
[Cl:20][c:21]1[n:22][cH:23][n:24][c:25]2[cH:26][cH:27][c:28](-[c:31]3[o:32][c:33]([CH3:36])[n:34][n:35]3)[cH:29][c:30]12.[F:1][c:2]1[c:3]([CH2:4][n:5]2[n:6][cH:7][c:8]3[cH:9][c:10]([NH2:14])[cH:11][cH:12][c:13]23)[cH:15][cH:16][cH:17][c:18]1[F:19]>>[ClH:20].[F:1][c:2]1[c:3]([CH2:4][n:5]2[n:6][cH:7][c:8]3[cH:9][c:10]([NH:14][c:21]4[n:22][cH:23][n:24][c:25]5[cH:26][cH:27][c:28](-[c:31]6[o:32][c:33]([CH3:36])[n:34][n:35]6)[cH:29][c:30]45)[cH:11][cH:12][c:13]23)[cH:15][cH:16][cH:17][c:18]1[F:19]

Participants

4

Reactant 2

HCID 219520591-(2,3-difluorobenzyl)-1H-indazol-5-amineHCID 226097254-Chloro-6-(5-methyl-1,3,4-oxadiazol-2-yl)quinazoline

Product 2

HCID 313Hydrochloric AcidHCID 22609774N-[1-[(2,3-difluorophenyl)methyl]indazol-5-yl]-6-(5-methyl-1,3,4-oxadiazol-2-yl)quinazolin-4-amine

Sources & evidence

ORD record
ord-1381d3ea8d2d410e810c0143f4d41405
Source dataset
Validation data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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