Pyrazole → (2-(1H-Pyrazol-1-YL)pyridin-4-YL)methanol

HRID 935279Notes

Reaction equation

HRID 935279 reaction equation
[Br:1][c:2]1[n:3][cH:4][cH:5][c:6]([CH2:8][OH:9])[cH:7]1.[C:15](=[O:16])([O-:17])[O-:18].[CH3:21][C:22]#[N:23].[Cs+:19].[Cs+:20].[nH:10]1[n:11][cH:12][cH:13][cH:14]1>>[c:2]1(-[n:10]2[n:11][cH:12][cH:13][cH:14]2)[n:3][cH:4][cH:5][c:6]([CH2:8][OH:9])[cH:7]1

Participants

6

Reactant 5

HCID 1048PyrazoleHCID 6342AcetonitrileHCID 19660Carbonate IonHCID 104967Cesium cation2×HCID 14512957(2-Bromopyridin-4-yl)methanol

Product 1

HCID 61256684(2-(1H-Pyrazol-1-YL)pyridin-4-YL)methanol

Sources & evidence

ORD record
ord-2d11623c9d554f5ba73e41fd90d49b30
Source dataset
Validation data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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