Chloroform → N-(2,3-dihydro(1,4)dioxino(2,3-c)pyridin-7-ylmethyl)-2,2,2-trifluoro-N-(piperidin-3-ylmethyl)acetamide
Reaction equation
[CH:33]([Cl:34])([Cl:35])[Cl:36].[O:1]1[CH2:2][CH2:3][O:4][c:5]2[cH:6][n:7][c:8]([CH2:11][N:12]([C:13]([C:14]([F:15])([F:16])[F:17])=[O:18])[CH2:19][CH:20]3[CH2:21][N:22]([C:26]([O:27][C:28]([CH3:29])([CH3:30])[CH3:31])=[O:32])[CH2:23][CH2:24][CH2:25]3)[cH:9][c:10]21.[OH:37][C:38]([C:39]([F:40])([F:41])[F:42])=[O:43]>>[O:1]1[CH2:2][CH2:3][O:4][c:5]2[cH:6][n:7][c:8]([CH2:11][N:12]([C:13]([C:14]([F:15])([F:16])[F:17])=[O:18])[CH2:19][CH:20]3[CH2:21][NH:22][CH2:23][CH2:24][CH2:25]3)[cH:9][c:10]21Participants
4
Reactant 3
Product 1
Sources & evidence
- ORD record
- ord-0008e0761d964d8ba26606606f475c27
- Source dataset
- Validation data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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