Dichloromethane → 3-(3,5-Difluoro-4-methoxybenzoyl)-2,3-dihydro-1,3-benzothiazole

HRID 935665Notes

Reaction equation

HRID 935665 reaction equation
[CH:18]([N:19]([CH:20]([CH3:21])[CH3:22])[CH2:23][CH3:24])([CH3:25])[CH3:26].[Cl:40][CH2:41][Cl:42].[F:27][c:28]1[cH:29][c:30]([C:31](=[O:32])[Cl:33])[cH:34][c:35]([F:39])[c:36]1[O:37][CH3:38].[NH2:10][c:11]1[cH:12][cH:13][cH:14][cH:15][c:16]1[SH:17].[S:1]1[CH2:2][NH:3][c:4]2[c:5]1[cH:6][cH:7][cH:8][cH:9]2>>[S:1]1[CH2:2][N:3]([C:31]([c:30]2[cH:29][c:28]([F:27])[c:36]([O:37][CH3:38])[c:35]([F:39])[cH:34]2)=[O:32])[c:4]2[c:5]1[cH:6][cH:7][cH:8][cH:9]2

Participants

6

Reactant 5

HCID 6344DichloromethaneHCID 87132-AminothiophenolHCID 81531DiisopropylethylamineHCID 96588BenzothiazolineHCID 177506623,5-Difluoro-4-methoxybenzoyl chloride

Product 1

HCID 681090913-(3,5-Difluoro-4-methoxybenzoyl)-2,3-dihydro-1,3-benzothiazole

Sources & evidence

ORD record
ord-0b0c513b3a2a4db290c892c5a24df395
Source dataset
Validation data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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