Dichloromethane → HCID 9844987, compound

HRID 935729Notes

Reaction equation

HRID 935729 reaction equation
[CH2:43]([Cl:44])[Cl:45].[CH3:32][CH2:33][N:34]([CH2:35][CH3:36])[CH2:37][CH3:38].[NH2:14][CH:15]1[CH2:16][O:17][c:18]2[c:19]([c:21]([N:25]3[CH2:26][CH2:27][N:28]([CH3:31])[CH2:29][CH2:30]3)[cH:22][cH:23][cH:24]2)[CH2:20]1.[OH:1][C:2](=[O:3])[c:4]1[cH:5][cH:6][c:7]([C:10]([F:11])([F:12])[F:13])[cH:8][cH:9]1.[S:39]([Cl:40])([Cl:41])=[O:42]>>[C:2](=[O:3])([c:4]1[cH:5][cH:6][c:7]([C:10]([F:11])([F:12])[F:13])[cH:8][cH:9]1)[NH:14][CH:15]1[CH2:16][O:17][c:18]2[c:19]([c:21]([N:25]3[CH2:26][CH2:27][N:28]([CH3:31])[CH2:29][CH2:30]3)[cH:22][cH:23][cH:24]2)[CH2:20]1

Participants

6

Reactant 5

HCID 6344DichloromethaneHCID 8471TriethylamineHCID 99664-(Trifluoromethyl)benzoic acidHCID 24386Thionyl ChlorideHCID 220640215-(4-methylpiperazin-1-yl)-3,4-dihydro-2H-chromen-3-amine

Product 1

HCID 9844987HCID 9844987, compound

Sources & evidence

ORD record
ord-f9db18de2fd747648e2a9fe81c5ba900
Source dataset
Validation data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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