Tetrahydrofuran → 2-Phenoxymethyl-1-(4-trifluoromethoxy-benzyl)-1H-benzoimidazole-5-carboxylic acid [2-(3-methoxy-phenyl)-ethyl]-amide
Reaction equation
[CH2:44]1[O:45][CH2:46][CH2:47][CH2:48]1.[CH3:33][O:34][c:35]1[cH:36][c:37]([CH2:38][CH2:39][NH2:40])[cH:41][cH:42][cH:43]1.[O:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1)[CH2:8][c:9]1[n:10][c:11]2[c:12]([n:13]1[CH2:14][c:15]1[cH:16][cH:17][c:18]([O:21][C:22]([F:23])([F:24])[F:25])[cH:19][cH:20]1)[cH:26][cH:27][c:28]([C:30](=[O:31])[OH:32])[cH:29]2>>[O:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1)[CH2:8][c:9]1[n:10][c:11]2[c:12]([n:13]1[CH2:14][c:15]1[cH:16][cH:17][c:18]([O:21][C:22]([F:23])([F:24])[F:25])[cH:19][cH:20]1)[cH:26][cH:27][c:28]([C:30](=[O:31])[NH:40][CH2:39][CH2:38][c:37]1[cH:36][c:35]([O:34][CH3:33])[cH:43][cH:42][cH:41]1)[cH:29]2Participants
4
Sources & evidence
- ORD record
- ord-e65c585f28624d47ac3b17fb97a84bbc
- Source dataset
- Validation data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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