Dimethylamine → 6-[cyclohexyl(cyclopropylmethyl)amino]-N-{4-[(dimethylamino)sulfonyl]-2-methylphenyl}pyrimidine-4-carboxamide

HRID 935824Notes

Reaction equation

HRID 935824 reaction equation
[CH2:35]1[O:36][CH2:37][CH2:38][CH2:39]1.[CH3:32][NH:33][CH3:34].[CH:1]1([N:7]([c:8]2[cH:9][c:10]([C:14](=[O:15])[NH:16][c:17]3[c:18]([CH3:27])[cH:19][c:20]([S:23](=[O:24])(=[O:25])[Cl:26])[cH:21][cH:22]3)[n:11][cH:12][n:13]2)[CH2:28][CH:29]2[CH2:30][CH2:31]2)[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6]1>>[CH:1]1([N:7]([c:8]2[cH:9][c:10]([C:14](=[O:15])[NH:16][c:17]3[c:18]([CH3:27])[cH:19][c:20]([S:23](=[O:24])(=[O:25])[N:33]([CH3:32])[CH3:34])[cH:21][cH:22]3)[n:11][cH:12][n:13]2)[CH2:28][CH:29]2[CH2:30][CH2:31]2)[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6]1

Participants

4

Reactant 3

HCID 674DimethylamineHCID 8028TetrahydrofuranHCID 594468814-[({6-[Cyclohexyl(cyclopropylmethyl)amino]pyrimidin-4-yl}carbonyl)amino]-3-methylbenzenesulfonyl chloride

Product 1

HCID 251829116-[cyclohexyl(cyclopropylmethyl)amino]-N-{4-[(dimethylamino)sulfonyl]-2-methylphenyl}pyrimidine-4-carboxamide

Sources & evidence

ORD record
ord-0ef8e9646d414461b297366d1a57ae1e
Source dataset
Validation data from https://doi.org/10.1039/C8SC04228D

Reaction notes

Loading…