Cyclopropylboronic acid → Ethyl 4-[2-[(6-cyclopropyl-2-phenylpyrimidine-4-carbonyl)amino]-5-[(2-methylpropan-2-yl)oxy]-5-oxopentanoyl]piperazine-1-carboxylate
Reaction equation
[CH2:1]([CH3:2])[O:3][C:4](=[O:5])[N:6]1[CH2:7][CH2:8][N:9]([C:12]([CH:13]([CH2:14][CH2:15][C:16](=[O:17])[O:18][C:19]([CH3:20])([CH3:21])[CH3:22])[NH:23][C:24](=[O:25])[c:26]2[n:27][c:28](-[c:33]3[cH:34][cH:35][cH:36][cH:37][cH:38]3)[n:29][c:30]([Cl:32])[cH:31]2)=[O:39])[CH2:10][CH2:11]1.[CH:40]1([B:43]([OH:44])[OH:45])[CH2:41][CH2:42]1>>[CH2:1]([CH3:2])[O:3][C:4](=[O:5])[N:6]1[CH2:7][CH2:8][N:9]([C:12]([CH:13]([CH2:14][CH2:15][C:16](=[O:17])[O:18][C:19]([CH3:20])([CH3:21])[CH3:22])[NH:23][C:24](=[O:25])[c:26]2[n:27][c:28](-[c:33]3[cH:34][cH:35][cH:36][cH:37][cH:38]3)[n:29][c:30]([CH:40]3[CH2:41][CH2:42]3)[cH:31]2)=[O:39])[CH2:10][CH2:11]1Participants
3
Reactant 2
Product 1
Sources & evidence
- ORD record
- ord-2c978737f32d4bd3a2421bf9bb29a27d
- Source dataset
- Validation data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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