Tetrahydrofuran → 3-Ethynylimidazo[1,2-b]pyridazine

HRID 935987Notes

Reaction equation

HRID 935987 reaction equation
[CH2:34]1[O:35][CH2:36][CH2:37][CH2:38]1.[CH3:17][CH2:18][CH2:19][CH2:20][N+:21]([CH2:22][CH2:23][CH2:24][CH3:25])([CH2:26][CH2:27][CH2:28][CH3:29])[CH2:30][CH2:31][CH2:32][CH3:33].[CH3:1][Si:2]([CH3:3])([CH3:4])[C:5]#[C:6][c:7]1[cH:8][n:9][c:10]2[n:11]1[n:12][cH:13][cH:14][cH:15]2.[F-:16]>>[CH:5]#[C:6][c:7]1[cH:8][n:9][c:10]2[n:11]1[n:12][cH:13][cH:14][cH:15]2

Participants

5

Reactant 4

HCID 8028TetrahydrofuranHCID 16028TetrabutylammoniumHCID 28179Fluoride IonHCID 667355693-((Trimethylsilyl)ethynyl)imidazo[1,2-b]pyridazine

Product 1

HCID 468387603-Ethynylimidazo[1,2-b]pyridazine

Sources & evidence

ORD record
ord-3e9d11408c654675a69ef81a73310ea1
Source dataset
Validation data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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