Hydrochloric Acid → Hydrochloric Acid

HRID 936024Notes

Reaction equation

HRID 936024 reaction equation
[C:1]([O:2][C:3](=[O:4])[NH:7][C:8]1=[N:13][C:12]([CH3:14])([c:15]2[cH:16][c:17]([Br:31])[cH:18][c:19]([NH:21][C:22](=[O:23])[c:24]3[n:25][cH:26][c:27]([Br:30])[cH:28][n:29]3)[cH:20]2)[CH2:11][O:10][CH2:9]1)([CH3:5])([CH3:6])[CH3:32].[ClH:39].[O:33]1[CH2:34][CH2:35][O:36][CH2:37][CH2:38]1>>[ClH:39].[NH2:7][C:8]1=[N:13][C:12]([CH3:14])([c:15]2[cH:16][c:17]([Br:31])[cH:18][c:19]([NH:21][C:22](=[O:23])[c:24]3[n:25][cH:26][c:27]([Br:30])[cH:28][n:29]3)[cH:20]2)[CH2:11][O:10][CH2:9]1

Participants

5

Reactant 3

HCID 313Hydrochloric AcidHCID 312751,4-DioxaneHCID 66665825tert-butyl N-[5-[3-bromo-5-[(5-bromopyrimidine-2-carbonyl)amino]phenyl]-5-methyl-2,6-dihydro-1,4-oxazin-3-yl]carbamate

Product 2

HCID 313Hydrochloric AcidHCID 66665817N-[3-(5-amino-3-methyl-2,6-dihydro-1,4-oxazin-3-yl)-5-bromophenyl]-5-bromopyrimidine-2-carboxamide

Sources & evidence

ORD record
ord-8daab0398bc74b1d99ccd099ffc3cd14
Source dataset
Validation data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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