Methyl iodide → 2-anilino-6,7-dimethyl-1-phenyl-1,8-naphthyridin-4(1H)-one
Reaction equation
[CH2:34]1[O:35][CH2:36][CH2:37][CH2:38]1.[CH3:27][CH2:28][CH2:29][CH2:30][Li:31].[CH3:32][I:33].[NH:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1)[c:8]1[n:9](-[c:21]2[cH:22][cH:23][cH:24][cH:25][cH:26]2)[c:10]2[n:11][c:12]([CH3:20])[c:13]([Br:19])[cH:14][c:15]2[c:16](=[O:18])[cH:17]1>>[NH:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1)[c:8]1[n:9](-[c:21]2[cH:22][cH:23][cH:24][cH:25][cH:26]2)[c:10]2[n:11][c:12]([CH3:20])[c:13]([CH3:27])[cH:14][c:15]2[c:16](=[O:18])[cH:17]1Participants
5
Sources & evidence
- ORD record
- ord-10458d5ed9b541079f715a42feec9622
- Source dataset
- Validation data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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