Hydrochloric Acid → 5-Chloro-N4-(1-methylpiperidin-4-yl)pyridine-2,4-diamine

HRID 936216Notes

Reaction equation

HRID 936216 reaction equation
[C:23](=[O:24])([O-:25])[O-:26].[Cl:1][c:2]1[c:3]([NH:15][CH:16]2[CH2:17][CH2:18][N:19]([CH3:22])[CH2:20][CH2:21]2)[cH:4][c:5]([NH:8][C:9](=[O:10])[C:11]([CH3:12])([CH3:13])[CH3:14])[n:6][cH:7]1.[ClH:29].[Na+:27].[Na+:28]>>[Cl:1][c:2]1[c:3]([NH:15][CH:16]2[CH2:17][CH2:18][N:19]([CH3:22])[CH2:20][CH2:21]2)[cH:4][c:5]([NH2:8])[n:6][cH:7]1

Participants

5

Reactant 4

HCID 313Hydrochloric AcidHCID 923Sodium ion2×HCID 19660Carbonate IonHCID 59613362N-(5-Chloro-4-(1-methylpiperidin-4-ylamino)pyridin-2-yl)pivalamide

Product 1

HCID 596134945-Chloro-N4-(1-methylpiperidin-4-yl)pyridine-2,4-diamine

Sources & evidence

ORD record
ord-31f1064a0dfa4c3b81b315d6f3055c9c
Source dataset
Validation data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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