Pyrrolidine → N,N-dimethyl-N'-[4-(1-methyl-4-{2-[4-(1-pyrrolidinylmethyl)phenyl]-1H-pyrrolo[2,3-b]pyridin-4-yl}-1H-pyrazol-3-yl)phenyl]urea
Reaction equation
[CH2:36]1[CH2:37][CH2:38][NH:39][CH2:40]1.[CH:1](=[O:2])[c:3]1[cH:4][cH:5][c:6](-[c:9]2[cH:10][c:11]3[c:12]([n:13][cH:14][cH:15][c:16]3-[c:17]3[c:18](-[c:23]4[cH:24][cH:25][c:26]([NH:29][C:30]([N:31]([CH3:32])[CH3:33])=[O:34])[cH:27][cH:28]4)[n:19][n:20]([CH3:22])[cH:21]3)[nH:35]2)[cH:7][cH:8]1>>[CH2:1]([c:3]1[cH:4][cH:5][c:6](-[c:9]2[cH:10][c:11]3[c:12]([n:13][cH:14][cH:15][c:16]3-[c:17]3[c:18](-[c:23]4[cH:24][cH:25][c:26]([NH:29][C:30]([N:31]([CH3:32])[CH3:33])=[O:34])[cH:27][cH:28]4)[n:19][n:20]([CH3:22])[cH:21]3)[nH:35]2)[cH:7][cH:8]1)[N:39]1[CH2:38][CH2:37][CH2:36][CH2:40]1Participants
3
Sources & evidence
- ORD record
- ord-7b71290b43dd456394ad7b771399be84
- Source dataset
- Validation data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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