Sodium ion → N-(3,4-Dichlorophenyl)-3-azaspiro[5.5]undecan-9-amine

HRID 936366Notes

Reaction equation

HRID 936366 reaction equation
[C:1]([O:2][C:3](=[O:4])[N:8]1[CH2:9][CH2:10][C:11]2([CH2:12][CH2:13]1)[CH2:14][CH2:15][CH:16]([NH:19][c:20]1[cH:21][c:22]([Cl:27])[c:23]([Cl:26])[cH:24][cH:25]1)[CH2:17][CH2:18]2)([CH3:5])([CH3:6])[CH3:7].[Cl:38][CH2:39][Cl:40].[Na+:37].[OH-:36].[OH2:35].[OH:28][C:29]([C:30]([F:31])([F:32])[F:33])=[O:34]>>[NH:8]1[CH2:9][CH2:10][C:11]2([CH2:12][CH2:13]1)[CH2:14][CH2:15][CH:16]([NH:19][c:20]1[cH:21][c:22]([Cl:27])[c:23]([Cl:26])[cH:24][cH:25]1)[CH2:17][CH2:18]2

Participants

7

Reactant 6

HCID 923Sodium ionHCID 961HydroxideHCID 962WaterHCID 6344DichloromethaneHCID 6422Trifluoroacetic acidHCID 674592189-(3,4-Dichloro-phenylamino)-3-aza-spiro[5.5]undecane-3-carboxylic acid tert-butyl ester

Product 1

HCID 16006654N-(3,4-Dichlorophenyl)-3-azaspiro[5.5]undecan-9-amine

Sources & evidence

ORD record
ord-931cc965697942f893a9c0c18599fd9b
Source dataset
Validation data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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