2-Fluorobenzonitrile → ethyl 1-(2-cyanophenyl)-4-piperidinecarboxylate

HRID 936396Notes

Reaction equation

HRID 936396 reaction equation
[F:1][c:2]1[c:3]([C:4]#[N:5])[cH:6][cH:7][cH:8][cH:9]1.[NH:10]1[CH2:11][CH2:12][CH:13]([C:14](=[O:15])[O:16][CH2:17][CH3:18])[CH2:19][CH2:20]1>>[c:2]1([N:10]2[CH2:11][CH2:12][CH:13]([C:14](=[O:15])[O:16][CH2:17][CH3:18])[CH2:19][CH2:20]2)[c:3]([C:4]#[N:5])[cH:6][cH:7][cH:8][cH:9]1

Participants

3

Reactant 2

HCID 678552-FluorobenzonitrileHCID 70770Ethyl 4-piperidinecarboxylate

Product 1

HCID 2764422ethyl 1-(2-cyanophenyl)-4-piperidinecarboxylate

Sources & evidence

ORD record
ord-bf3911a6e9e04dc2bd79a9c2fab006d3
Source dataset
Validation data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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