Sodium ion → 2,2,2-Trichloroethyl 3-tert-butyl-1-(4-cyanophenyl)-1H-pyrazol-5-ylcarbamate

HRID 936442Notes

Reaction equation

HRID 936442 reaction equation
[C:21]([O:22][CH2:23][C:24]([Cl:25])([Cl:26])[Cl:27])(=[O:28])[Cl:29].[CH3:30][CH2:31][O:32][C:33](=[O:34])[CH3:35].[NH2:1][c:2]1[cH:3][c:4]([C:15]([CH3:16])([CH3:17])[CH3:18])[n:5][n:6]1-[c:7]1[cH:8][cH:9][c:10]([C:11]#[N:12])[cH:13][cH:14]1.[Na+:20].[OH-:19]>>[NH:1]([c:2]1[cH:3][c:4]([C:15]([CH3:16])([CH3:17])[CH3:18])[n:5][n:6]1-[c:7]1[cH:8][cH:9][c:10]([C:11]#[N:12])[cH:13][cH:14]1)[C:21]([O:22][CH2:23][C:24]([Cl:25])([Cl:26])[Cl:27])=[O:28]

Participants

6

Reactant 5

HCID 923Sodium ionHCID 961HydroxideHCID 8857Ethyl AcetateHCID 870632,2,2-Trichloroethyl chloroformateHCID 71470834-(5-Amino-3-tert-butyl-1H-pyrazol-1-yl)benzonitrile

Product 1

HCID 687825092,2,2-Trichloroethyl 3-tert-butyl-1-(4-cyanophenyl)-1H-pyrazol-5-ylcarbamate

Sources & evidence

ORD record
ord-6b38b4ebd99246ca970bf815c70b4bb7
Source dataset
Validation data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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