Dimethylhydantoin → Nilutamide

HRID 936513Notes

Reaction equation

HRID 936513 reaction equation
[CH3:14][C:15]1([CH3:22])[C:16](=[O:21])[NH:17][C:18](=[O:20])[NH:19]1.[N+:23](=[O:24])([O-:25])[c:26]1[c:27]([C:33]([F:34])([F:35])[F:36])[cH:28][c:29]([Cl:32])[cH:30][cH:31]1.[c:1]1([O:2][c:3]2[cH:4][cH:5][cH:6][cH:7][cH:8]2)[cH:9][cH:10][cH:11][cH:12][cH:13]1>>[CH3:14][C:15]1([CH3:22])[C:16](=[O:21])[N:17]([c:29]2[cH:28][c:27]([C:33]([F:34])([F:35])[F:36])[c:26]([N+:23](=[O:24])[O-:25])[cH:31][cH:30]2)[C:18](=[O:20])[NH:19]1

Participants

4

Reactant 3

HCID 6491DimethylhydantoinHCID 7583Diphenyl EtherHCID 670525-Chloro-2-nitrobenzotrifluoride

Product 1

HCID 4493Nilutamide

Sources & evidence

ORD record
ord-e3ae78ed7c064875ae2c04ccacda9d7a
Source dataset
Validation data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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