Dichloromethane → 6-(3-Aminopyrrolidin-1-yl)nicotinonitrile
Reaction equation
[C:8]([O:9][C:10](=[O:11])[NH:14][CH:15]1[CH2:16][N:17]([c:20]2[n:21][cH:22][c:23]([C:26]#[N:27])[cH:24][cH:25]2)[CH2:18][CH2:19]1)([CH3:12])([CH3:13])[CH3:28].[Cl:29][CH2:30][Cl:31].[OH:1][C:2]([C:3]([F:4])([F:5])[F:6])=[O:7]>>[NH2:14][CH:15]1[CH2:16][N:17]([c:20]2[n:21][cH:22][c:23]([C:26]#[N:27])[cH:24][cH:25]2)[CH2:18][CH2:19]1Participants
4
Sources & evidence
- ORD record
- ord-dde70b1232ff4858aa3bf103f61e65a1
- Source dataset
- Validation data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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