Water → Ethyl 2-chloro-4-(4-fluorophenyl)-5-oxazolebutanoate

HRID 93715Notes

Reaction equation

HRID 93715 reaction equation
[F:1][c:2]1[cH:3][cH:4][c:5](-[c:8]2[nH:9][c:10](=[O:21])[o:11][c:12]2[CH2:13][CH2:14][CH2:15][C:16](=[O:17])[O:18][CH2:19][CH3:20])[cH:6][cH:7]1.[OH2:33].[P:22]([Cl:23])([Cl:24])([Cl:25])=[O:26].[cH:27]1[cH:28][cH:29][n:30][cH:31][cH:32]1>>[F:1][c:2]1[cH:3][cH:4][c:5](-[c:8]2[n:9][c:10]([Cl:24])[o:11][c:12]2[CH2:13][CH2:14][CH2:15][C:16](=[O:17])[O:18][CH2:19][CH3:20])[cH:6][cH:7]1

Participants

5

Reactant 4

HCID 962WaterHCID 1049PyridineHCID 24813Phosphorus oxychlorideHCID 18174763Ethyl 4-[4-(4-fluorophenyl)-2-oxo-4-oxazolin-5-yl]butanoate

Product 1

HCID 18174687Ethyl 2-chloro-4-(4-fluorophenyl)-5-oxazolebutanoate

Sources & evidence

ORD record
ord-b6b2a27723ed48dc877ec399f5c2c925
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (2/10)

Reaction notes

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