HRID937284

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID6344

Dichloromethane

CH2Cl2

HCID81531

Diisopropylethylamine

C8H19N

结构：CC1=C(C(=O)O)C(c2ccc(F)c(F)c2)NC(=O)N1

HCID18326575

4-(3,4-Difluorophenyl)-6-methyl-2-oxo-1,2,3,4-tetrahydropyrimidine-5-carboxylic acid

C12H10F2N2O3

HCID57755851

未命名化合物

PRODUCTS

生成物

结构：CC1=C(C(=O)Nc2ccc3[nH]nc(Nc4cccc(F)c4)c3c2)C(c2ccc(F)c(F)c2)NC(=O)N1

HCID57755873

未命名化合物

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-8bbc726ed6424c17af9415405e7486c8
来源数据集: Validation data from https://doi.org/10.1039/C8SC04228D
DOI: 10.1039/C8SC04228D
来源说明: Validation data from https://doi.org/10.1039/C8SC04228D

反应 SMILES

[CH2:47]([Cl:48])[Cl:49].[CH:38]([N:39]([CH:40]([CH3:41])[CH3:42])[CH2:43][CH3:44])([CH3:45])[CH3:46].[F:1][c:2]1[cH:3][c:4]([CH:9]2[NH:10][C:11](=[O:19])[NH:12][C:13]([CH3:18])=[C:14]2[C:15](=[O:16])[OH:17])[cH:5][cH:6][c:7]1[F:8].[F:20][c:21]1[cH:22][c:23]([NH:27][c:28]2[n:29][nH:30][c:31]3[cH:32][cH:33][c:34]([NH2:37])[cH:35][c:36]23)[cH:24][cH:25][cH:26]1>>[F:1][c:2]1[cH:3][c:4]([CH:9]2[NH:10][C:11](=[O:19])[NH:12][C:13]([CH3:18])=[C:14]2[C:15](=[O:17])[NH:37][c:34]2[cH:33][cH:32][c:31]3[nH:30][n:29][c:28]([NH:27][c:23]4[cH:22][c:21]([F:20])[cH:26][cH:25][cH:24]4)[c:36]3[cH:35]2)[cH:5][cH:6][c:7]1[F:8]