Tetrahydrofuran → tert-butyl (2RS,5SR)-1-{2-[3-(3-methylphenyl)ureido]acetyl}-5-phenylprolinate
Reaction equation
[CH3:1][c:2]1[cH:3][c:4]([N:8]=[C:9]=[O:10])[cH:5][cH:6][cH:7]1.[NH2:11][CH2:12][C:13](=[O:14])[N:15]1[CH:16]([C:17](=[O:18])[O:19][C:20]([CH3:21])([CH3:22])[CH3:23])[CH2:24][CH2:25][CH:26]1[c:27]1[cH:28][cH:29][cH:30][cH:31][cH:32]1.[O:33]1[CH2:34][CH2:35][CH2:36][CH2:37]1>>[CH3:1][c:2]1[cH:3][c:4]([NH:8][C:9](=[O:10])[NH:11][CH2:12][C:13](=[O:14])[N:15]2[CH:16]([C:17](=[O:18])[O:19][C:20]([CH3:21])([CH3:22])[CH3:23])[CH2:24][CH2:25][CH:26]2[c:27]2[cH:28][cH:29][cH:30][cH:31][cH:32]2)[cH:5][cH:6][cH:7]1Participants
4
Sources & evidence
- ORD record
- ord-a23a94e848bf489e87452eefe32b8b75
- Source dataset
- Validation data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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