4-Hydroxyphenylboronic acid → 1-Cyclohexyl-3-(3,5-dichloro-4'-hydroxy-biphenyl-4-ylmethyl)-pyrrolidin-2-one
Reaction equation
[F:1][C:2]([F:3])([F:4])[S:5]([O:6][c:7]1[cH:8][c:9]([Cl:27])[c:10]([CH2:14][CH:15]2[C:16](=[O:26])[N:17]([CH:20]3[CH2:21][CH2:22][CH2:23][CH2:24][CH2:25]3)[CH2:18][CH2:19]2)[c:11]([Cl:13])[cH:12]1)(=[O:28])=[O:29].[OH:30][c:31]1[cH:32][cH:33][c:34]([B:37]([OH:38])[OH:39])[cH:35][cH:36]1>>[c:7]1(-[c:34]2[cH:33][cH:32][c:31]([OH:30])[cH:36][cH:35]2)[cH:8][c:9]([Cl:27])[c:10]([CH2:14][CH:15]2[C:16](=[O:26])[N:17]([CH:20]3[CH2:21][CH2:22][CH2:23][CH2:24][CH2:25]3)[CH2:18][CH2:19]2)[c:11]([Cl:13])[cH:12]1Participants
3
Sources & evidence
- ORD record
- ord-f10bd5c289fd4637a80211da0b771eaf
- Source dataset
- Validation data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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