Tetrahydrofuran → tert-Butyl 4-(4-aminophenyl)piperazine-1-carboxylate

HRID 937366Notes

Reaction equation

HRID 937366 reaction equation
[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[CH2:9][CH2:10][N:11]([c:14]2[cH:15][cH:16][c:17]([N+:20]([O-:21])=[O:22])[cH:18][cH:19]2)[CH2:12][CH2:13]1.[H:23][H:24].[O:25]1[CH2:26][CH2:27][CH2:28][CH2:29]1>>[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[CH2:9][CH2:10][N:11]([c:14]2[cH:15][cH:16][c:17]([NH2:20])[cH:18][cH:19]2)[CH2:12][CH2:13]1

Participants

4

Reactant 3

HCID 8028TetrahydrofuranHCID 33806961-Boc-4-(4-Nitrophenyl)piperazineHCID 178418361HCID 178418361, compound

Product 1

HCID 11011301tert-Butyl 4-(4-aminophenyl)piperazine-1-carboxylate

Sources & evidence

ORD record
ord-f22dfc86bbd8409298d197520e1d40e5
Source dataset
Validation data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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