Tetrahydrofuran → Tert-butyl 4-acetyl-3-methylpiperidine-1-carboxylate

HRID 937371Notes

Reaction equation

HRID 937371 reaction equation
[CH2:24]1[O:25][CH2:26][CH2:27][CH2:28]1.[CH3:1][Mg:2][Cl:3].[CH3:4][O:5][N:6]([C:7](=[O:8])[CH:9]1[CH:10]([CH3:22])[CH2:11][N:12]([C:15](=[O:16])[O:17][C:18]([CH3:19])([CH3:20])[CH3:21])[CH2:13][CH2:14]1)[CH3:23]>>[CH3:1][C:7](=[O:8])[CH:9]1[CH:10]([CH3:22])[CH2:11][N:12]([C:15](=[O:16])[O:17][C:18]([CH3:19])([CH3:20])[CH3:21])[CH2:13][CH2:14]1

Participants

4

Reactant 3

HCID 8028TetrahydrofuranHCID 86601647Tert-butyl 4-(methoxy(methyl)carbamoyl)-3-methylpiperidine-1-carboxylateHCID 178418332HCID 178418332, compound

Product 1

HCID 57741702Tert-butyl 4-acetyl-3-methylpiperidine-1-carboxylate

Sources & evidence

ORD record
ord-596167b2f89d407799fa8c9d311f996c
Source dataset
Validation data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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