Methanol → 4,4-Dimethyl-7-{2-[(pyridazin-4-ylmethylene)-amino]-benzoylamino}-3,4-dihydro-1H-isoquinoline-2-carboxylic acid tert-butyl ester

HRID 937380Notes

Reaction equation

[BH4-:49].[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[CH2:9][c:10]2[cH:11][c:12]([NH:20][C:21]([c:22]3[c:23]([NH2:28])[cH:24][cH:25][cH:26][cH:27]3)=[O:29])[cH:13][cH:14][c:15]2[C:16]([CH3:18])([CH3:19])[CH2:17]1.[CH3:51][c:52]1[cH:53][cH:54][cH:55][cH:56][cH:57]1.[CH3:61][OH:62].[Cl:58][CH2:59][Cl:60].[Na+:50].[c:38]1([CH3:39])[cH:40][cH:41][c:42]([S:43]([OH:44])(=[O:45])=[O:46])[cH:47][cH:48]1.[n:30]1[n:31][cH:32][c:33]([CH:36]=[O:37])[cH:34][cH:35]1>>[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[CH2:9][c:10]2[cH:11][c:12]([NH:20][C:21]([c:22]3[c:23]([N:28]=[CH:36][c:33]4[cH:32][n:31][n:30][cH:35][cH:34]4)[cH:24][cH:25][cH:26][cH:27]3)=[O:29])[cH:13][cH:14][c:15]2[C:16]([CH3:18])([CH3:19])[CH2:17]1