Dichloromethane → (4-Isopropyl-phenyl)-[2-(3-nitro-benzylamino)-5-propargyloxy-phenyl]-methanone

HRID 937411Notes

Reaction equation

HRID 937411 reaction equation
[CH2:43]([Cl:44])[Cl:45].[CH:34]([N:35]([CH2:36][CH3:37])[CH:38]([CH3:39])[CH3:40])([CH3:41])[CH3:42].[N+:23](=[O:24])([O-:25])[c:26]1[cH:27][c:28]([CH2:29][Br:30])[cH:31][cH:32][cH:33]1.[NH2:1][c:2]1[c:3]([C:12](=[O:13])[c:14]2[cH:15][cH:16][c:17]([CH:20]([CH3:21])[CH3:22])[cH:18][cH:19]2)[cH:4][c:5]([O:8][CH2:9][C:10]#[CH:11])[cH:6][cH:7]1>>[NH:1]([c:2]1[c:3]([C:12](=[O:13])[c:14]2[cH:15][cH:16][c:17]([CH:20]([CH3:21])[CH3:22])[cH:18][cH:19]2)[cH:4][c:5]([O:8][CH2:9][C:10]#[CH:11])[cH:6][cH:7]1)[CH2:29][c:28]1[cH:27][c:26]([N+:23](=[O:24])[O-:25])[cH:33][cH:32][cH:31]1

Participants

5

Reactant 4

HCID 6344DichloromethaneHCID 77568Benzene, 1-(bromomethyl)-3-nitro-HCID 81531DiisopropylethylamineHCID 45139628(2-Amino-5-(prop-2-yn-1-yloxy)phenyl)(4-isopropylphenyl)methanone

Product 1

HCID 86761896(4-Isopropyl-phenyl)-[2-(3-nitro-benzylamino)-5-propargyloxy-phenyl]-methanone

Sources & evidence

ORD record
ord-6b79ec192da14df186684548dad9b3ee
Source dataset
Validation data from https://doi.org/10.1039/C8SC04228D

Reaction notes

Loading…