Sodium ion → 4-amino-5-(4-phenoxyphenyl)-7-(3-tetrahydrofuryl)-7H-pyrrolo[2,3-d]pyrimidine

HRID 937473Notes

Reaction equation

HRID 937473 reaction equation
[H-:1].[NH2:3][c:4]1[c:5]2[c:6]([n:7][cH:8][n:9]1)[nH:10][cH:11][c:12]2-[c:13]1[cH:14][cH:15][c:16]([O:19][c:20]2[cH:21][cH:22][cH:23][cH:24][cH:25]2)[cH:17][cH:18]1.[Na+:2].[O:42]=[CH:43][N:44]([CH3:45])[CH3:46].[S:26]([O:27][CH:37]1[CH2:38][O:39][CH2:40][CH2:41]1)([c:28]1[cH:29][cH:30][c:31]([CH3:32])[cH:33][cH:34]1)(=[O:35])=[O:36]>>[NH2:3][c:4]1[c:5]2[c:6]([n:7][cH:8][n:9]1)[n:10]([CH:37]1[CH2:38][O:39][CH2:40][CH2:41]1)[cH:11][c:12]2-[c:13]1[cH:14][cH:15][c:16]([O:19][c:20]2[cH:21][cH:22][cH:23][cH:24][cH:25]2)[cH:17][cH:18]1

Participants

6

Reactant 5

HCID 923Sodium ionHCID 6228DimethylformamideHCID 166653HydrideHCID 120422345-(4-phenoxyphenyl)-7H-pyrrolo[2,3-d]pyrimidin-4-ylamineHCID 13837325Tetrahydrofuran-3-yl 4-methylbenzenesulfonate

Product 1

HCID 227363324-amino-5-(4-phenoxyphenyl)-7-(3-tetrahydrofuryl)-7H-pyrrolo[2,3-d]pyrimidine

Sources & evidence

ORD record
ord-18004010db0e49f1a0c544a988473492
Source dataset
Validation data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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