Bromide ion → 3'-Chloro-5'-methoxyacetophenone

HRID 937676Notes

Reaction equation

HRID 937676 reaction equation
[Br-:22].[CH3:18][NH:19][O:20][CH3:21].[CH3:23][Mg+:24].[Cl:1][c:2]1[cH:3][c:4]([C:5](=[O:6])[OH:7])[cH:8][c:9]([O:11][CH3:12])[cH:10]1.[ClH:17].[S:13]([Cl:14])([Cl:15])=[O:16]>>[Cl:1][c:2]1[cH:3][c:4]([C:5](=[O:7])[CH3:18])[cH:8][c:9]([O:11][CH3:12])[cH:10]1

Participants

7

Reactant 6

HCID 259Bromide ionHCID 313Hydrochloric AcidHCID 14232N,O-DimethylhydroxylamineHCID 24386Thionyl ChlorideHCID 129093413-Chloro-5-methoxybenzoic acidHCID 178477777HCID 178477777, compound

Product 1

HCID 134938543'-Chloro-5'-methoxyacetophenone

Sources & evidence

ORD record
ord-757a585bfeda421292e8b70aef2829db
Source dataset
Validation data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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