Dichloromethane → Trifluoroacetic acid

HRID 937890Notes

Reaction equation

HRID 937890 reaction equation
[Cl:1][c:2]1[n:3][cH:4][n:5](-[c:7]2[c:8]([O:43][CH3:44])[cH:9][c:10]([NH:13][c:14]3[n:15][c:16]([N:30]4[CH2:31][CH2:32][N:33]([C:36]([O:37][C:38]([CH3:39])([CH3:40])[CH3:41])=[O:42])[CH2:34][CH2:35]4)[c:17]4[c:18]([n:19]3)[CH:20]([c:23]3[cH:24][cH:25][c:26]([F:29])[cH:27][cH:28]3)[CH2:21][CH2:22]4)[cH:11][cH:12]2)[cH:6]1.[Cl:52][CH2:53][Cl:54].[F:45][C:46]([C:47](=[O:48])[OH:49])([F:50])[F:51]>>[Cl:1][c:2]1[n:3][cH:4][n:5](-[c:7]2[c:8]([O:43][CH3:44])[cH:9][c:10]([NH:13][c:14]3[n:15][c:16]([N:30]4[CH2:31][CH2:32][NH:33][CH2:34][CH2:35]4)[c:17]4[c:18]([n:19]3)[CH:20]([c:23]3[cH:24][cH:25][c:26]([F:29])[cH:27][cH:28]3)[CH2:21][CH2:22]4)[cH:11][cH:12]2)[cH:6]1.[F:45][C:46]([C:47](=[O:48])[OH:49])([F:50])[F:51]

Participants

5

Reactant 3

HCID 6344DichloromethaneHCID 6422Trifluoroacetic acidHCID 58075688HCID 58075688, compound

Product 2

HCID 6422Trifluoroacetic acidHCID 66709099HCID 66709099, compound

Sources & evidence

ORD record
ord-d78d57dc5afd42fb9b5049bfc15e8adb
Source dataset
Validation data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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