Phosphorus oxychloride → Ethyl 4-chloro-6-(trifluoromethoxy)quinoline-3-carboxylate
Reaction equation
[F:1][C:2]([O:3][c:4]1[cH:5][c:6]2[c:7]([OH:19])[c:8]([C:14](=[O:15])[O:16][CH2:17][CH3:18])[cH:9][n:10][c:11]2[cH:12][cH:13]1)([F:20])[F:21].[P:22]([Cl:23])([Cl:24])([Cl:25])=[O:26]>>[F:1][C:2]([O:3][c:4]1[cH:5][c:6]2[c:7]([Cl:24])[c:8]([C:14](=[O:15])[O:16][CH2:17][CH3:18])[cH:9][n:10][c:11]2[cH:12][cH:13]1)([F:20])[F:21]Participants
3
Sources & evidence
- ORD record
- ord-6cd4ce62a0114cffa16a02ef2de2129e
- Source dataset
- Validation data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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