Methanol → 6'-methoxy-7',8'-dimethyl-2',4'-dihydro-1'H-spiro[cyclobutane-1,3'-quinolin]-4'-ol
Reaction equation
[BH4-:19].[CH2:21]1[O:22][CH2:23][CH2:24][CH2:25]1.[CH3:1][O:2][c:3]1[cH:4][c:5]2[c:13]([c:14]([CH3:17])[c:15]1[CH3:16])[NH:12][CH2:11][C:7]1([C:6]2=[O:18])[CH2:8][CH2:9][CH2:10]1.[CH3:26][OH:27].[Na+:20]>>[CH3:1][O:2][c:3]1[cH:4][c:5]2[c:13]([c:14]([CH3:17])[c:15]1[CH3:16])[NH:12][CH2:11][C:7]1([CH:6]2[OH:18])[CH2:8][CH2:9][CH2:10]1Participants
6
Sources & evidence
- ORD record
- ord-dd1050b60cab4a66865c84a004445015
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (2/10)
Reaction notes
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