Dichloromethane → Biphenyl-2-ylcarbamic acid 1-{2-[(3-aminopropyl)methylcarbamoyl]ethyl}piperidin-4-yl ester
Reaction equation
[CH2:50]1[CH2:51][CH2:52][NH:53][CH2:54][CH2:55]1.[Cl:56][CH2:57][Cl:58].[cH:1]1[c:2]2[c:14]([cH:15][cH:16][cH:17]1)-[c:9]1[c:8]([cH:13][cH:12][cH:11][cH:10]1)[CH:3]2[CH2:4][O:5][C:6](=[O:7])[NH:18][CH2:19][CH2:20][CH2:21][N:22]([C:23](=[O:24])[CH2:25][CH2:26][N:27]1[CH2:28][CH2:29][CH:30]([O:33][C:34]([NH:35][c:36]2[c:37](-[c:42]3[cH:43][cH:44][cH:45][cH:46][cH:47]3)[cH:38][cH:39][cH:40][cH:41]2)=[O:48])[CH2:31][CH2:32]1)[CH3:49]>>[NH2:18][CH2:19][CH2:20][CH2:21][N:22]([C:23](=[O:24])[CH2:25][CH2:26][N:27]1[CH2:28][CH2:29][CH:30]([O:33][C:34]([NH:35][c:36]2[c:37](-[c:42]3[cH:43][cH:44][cH:45][cH:46][cH:47]3)[cH:38][cH:39][cH:40][cH:41]2)=[O:48])[CH2:31][CH2:32]1)[CH3:49]Participants
4
Reactant 3
Product 1
Sources & evidence
- ORD record
- ord-191b6b05fa9141eba278c13316e760bd
- Source dataset
- Validation data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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