Dichloromethane → Piperidine-3-carboxylic acid [4-phenyl-1-(3-phenyl-propyl)-butyl]-amide

HRID 938103Notes

Reaction equation

HRID 938103 reaction equation
[CH2:43]([Cl:44])[Cl:45].[OH:36][C:37]([C:38]([F:39])([F:40])[F:41])=[O:42].[c:1]1([CH2:7][CH2:8][CH2:9][CH:10]([CH2:11][CH2:12][CH2:13][c:14]2[cH:15][cH:16][cH:17][cH:18][cH:19]2)[NH:20][C:21](=[O:22])[CH:23]2[CH2:24][N:25]([C:29]([O:30][C:31]([CH3:32])([CH3:33])[CH3:34])=[O:35])[CH2:26][CH2:27][CH2:28]2)[cH:2][cH:3][cH:4][cH:5][cH:6]1>>[c:1]1([CH2:7][CH2:8][CH2:9][CH:10]([CH2:11][CH2:12][CH2:13][c:14]2[cH:15][cH:16][cH:17][cH:18][cH:19]2)[NH:20][C:21](=[O:22])[CH:23]2[CH2:24][NH:25][CH2:26][CH2:27][CH2:28]2)[cH:2][cH:3][cH:4][cH:5][cH:6]1

Participants

4

Reactant 3

HCID 6344DichloromethaneHCID 6422Trifluoroacetic acidHCID 121367623-[4-Phenyl-1-(3-phenyl-propyl)-butylcarbamoyl]-piperidine-1-carboxylic acid tert-butyl ester

Product 1

HCID 12020263Piperidine-3-carboxylic acid [4-phenyl-1-(3-phenyl-propyl)-butyl]-amide

Sources & evidence

ORD record
ord-9ba110e6e1f54964b0fd343c7cb8ca91
Source dataset
Validation data from https://doi.org/10.1039/C8SC04228D

Reaction notes

Loading…