Ethyl Acetate → Tert-butyl 4-(2-methoxyphenyl)piperidine-1-carboxylate

HRID 938135Notes

Reaction equation

HRID 938135 reaction equation
[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[CH2:9][CH2:10][C:11]([c:14]2[c:15]([O:20][CH3:21])[cH:16][cH:17][cH:18][cH:19]2)=[CH:12][CH2:13]1.[CH3:22][CH2:23][O:24][C:25]([CH3:26])=[O:27]>>[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[CH2:9][CH2:10][CH:11]([c:14]2[c:15]([O:20][CH3:21])[cH:16][cH:17][cH:18][cH:19]2)[CH2:12][CH2:13]1

Participants

3

Reactant 2

HCID 8857Ethyl AcetateHCID 22629561tert-butyl 4-(2-methoxyphenyl)-5,6-dihydropyridine-1(2H)-carboxylate

Product 1

HCID 22629567Tert-butyl 4-(2-methoxyphenyl)piperidine-1-carboxylate

Sources & evidence

ORD record
ord-eb0757bc680445d6aba089e147c467d9
Source dataset
Validation data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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