Dichloromethane → 1-(4-(3-(Aminomethyl)-[1,2,4]triazolo[4,3-b]pyridazin-6-yl)-2-fluorophenyl)pyrrolidin-2-one
Reaction equation
[Cl:39][CH2:40][Cl:41].[F:1][c:2]1[cH:3][c:4](-[c:14]2[cH:15][cH:16][c:17]3[n:18]([n:19]2)[c:20]([CH2:23][NH:24][C:25](=[O:26])[O:27][C:28]([CH3:29])([CH3:30])[CH3:31])[n:21][n:22]3)[cH:5][cH:6][c:7]1[N:8]1[C:9](=[O:13])[CH2:10][CH2:11][CH2:12]1.[F:32][C:33]([F:34])([F:35])[C:36]([OH:37])=[O:38]>>[F:1][c:2]1[cH:3][c:4](-[c:14]2[cH:15][cH:16][c:17]3[n:18]([n:19]2)[c:20]([CH2:23][NH2:24])[n:21][n:22]3)[cH:5][cH:6][c:7]1[N:8]1[C:9](=[O:13])[CH2:10][CH2:11][CH2:12]1Participants
4
Sources & evidence
- ORD record
- ord-976cf92e121a49d7a09b5d1c6e0d477a
- Source dataset
- Validation data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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