Potassium Cation → 2-((2-Chloro-5-(trifluoromethyl)pyrimidin-4-yl)amino)-N-methylbenzamide

HRID 938416Notes

Reaction equation

HRID 938416 reaction equation
[CH3:26][C:27]#[N:28].[Cl:1][c:2]1[n:3][cH:4][c:5]([C:9]([F:10])([F:11])[F:12])[c:6]([Cl:8])[n:7]1.[K+:25].[NH2:13][c:14]1[c:15]([C:16](=[O:17])[NH:18][CH3:19])[cH:20][cH:21][cH:22][cH:23]1.[OH-:24]>>[Cl:1][c:2]1[n:3][cH:4][c:5]([C:9]([F:10])([F:11])[F:12])[c:6]([NH:13][c:14]2[c:15]([C:16](=[O:17])[NH:18][CH3:19])[cH:20][cH:21][cH:22][cH:23]2)[n:7]1

Participants

6

Reactant 5

HCID 813Potassium CationHCID 961HydroxideHCID 6342AcetonitrileHCID 3080722-Amino-N-methylbenzamideHCID 27827742,4-Dichloro-5-(trifluoromethyl)pyrimidine

Product 1

HCID 866338612-((2-Chloro-5-(trifluoromethyl)pyrimidin-4-yl)amino)-N-methylbenzamide

Sources & evidence

ORD record
ord-ef8c98d8d0854766bfba3b9a2c6770d8
Source dataset
Validation data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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